No. 10 Penn State Football at No. 5 Michigan Betting Line, Odds, Prediction, More

No. 10 Penn State Football travels to take on No. 5 Michigan, in a top-10 matchup between Big Ten powers, on Saturday, Oct. 15, 2022 at noon on FOX.

The Nittany Lions are coming off a bye week, and aim to make a significant statement in the championship picture, against Jim Harbaugh’s Wolverines.

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Here’s a look at everything you need to know about No. 10 Penn State Football at No. 5 Michigan

Penn State Football Injury Report

Jerry Cross TE Ques – Undisclosed

Jaden Dottin WR Ques – Undisclosed

Zuriah Fisher DE Out Indefinitely – Knee

Michigan Injury Report

Erick All TE Ques – Undisclosed

Roman Wilson WR Ques – Undisclosed

William Wagner LS Out for Season – Undisclosed

Caden Kolesar DB Out for Season – Knee

Nikhai Hill-Green LB Out Indefinitely – Lower Body

Cade McNamara QB Out Indefinitely – Leg

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Penn State Football vs. Michigan Spread

Penn State Football (+7) vs. Michigan

Penn State Football enters Saturday’s matchup as a 7-point underdog. This will be the first game of the season that the Nittany Lions will enter as an underdog. Penn State is 3-2 ATS, while Michigan is 3-3.

Penn State Football Moneyline: +220

Placing a $100 bet on Penn State Football to knock off Michigan, straight up on the moneyline, would pay $220. Michigan leads the all-time series 15-10 and are 8-4 in Ann Arbor.

The last matchup was in 2021 resulting in a 21-17 Wolverine victory in State College.

Penn State Football vs. Michigan over/under: 52

The over has hit in 3 out of 5 of Penn State’s games, while the Wolverines have hit the over in 1 of 6. The over has hit in 7 of the previous 10 matchups with Michigan.

Picks for the Week

The Nittany Lions have been poor off bye weeks in the James Franklin era. Pair that with a difficult time winning at Michigan and this matchup becomes rather unfavorable.

The Wolverines have not played a team as talented as Penn State Football this season. This game will come down to how well Sean Clifford and the offense can move the ball.

A first loss for the Nittany Lions is most likely on the table, given the environment and previous results at the Big House.

However, the over is always played when these 2 teams meet, and the games can often result in blowouts or shootouts.

Prediction: Michigan 35, Penn State Football 24

Big Ten Pick of the Week

Minnesota vs Illinois (+6.5)

The Gophers will look to rebound off their loss to Purdue with an increasingly difficult matchup against the Illini. Illinois is 5-1 on the season with their only loss on a last second drive to Indiana.

The Illini have already defeated traditional Big 10 West powers in Wisconsin and Iowa. Illinois is 4-2 ATS and the Gophers are 4-1.

Expect Illinois to cover this spread and possibly come out with the outright victory.